The science of AEVUM

Measured, notguessed.

Most medicine waits for symptoms. We measure the body decades earlier — over 1,284 biomarkers across every major system, read against the research and modelled into a single, honest picture of how you are aging.

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Biomarkers per assessment

6 systems

Measured in depth

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Peer-reviewed methods

Close-up of a precise, non-invasive clinical blood draw at AEVUM

Measurement precision

±0.3yrs

Biological-age model, validated against a 12,000-person cohort.

Our methodology

Three principles behind every number.

Precision health is not more tests for their own sake. It is the discipline of measuring the right things, deeply, again and again — and reading them honestly against the science.

01

Breadth before suspicion

We do not wait for a symptom to point us somewhere. Every system is measured every time — so the quiet, early signal is never missed because no one thought to look.

02

Depth that imaging allows

Whole-body MRI, cardiac imaging, and advanced blood and genomic panels see structure and function the standard annual physical cannot — at the resolution research now demands.

03

Your line, over time

A single reading is a dot. We re-test on schedule and model the trajectory, so the plan answers to your body — not to the population average it was first compared against.

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Biomarkers per scan

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Total scan time

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Radiation (MRI-based)

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Clinicians & scientists

Health, over time

The point is not a number.It is the direction.

+34

Points gained · 24 months

Composite health score

Today · 92
100806040Baseline scan6-month check1-year re-test18-monthToday · 92Jan 2023Jan 2025

Every marker is mapped to one of three zones. The chart is the story those zones tell as your plan takes effect — and where we focus next.

  • Optimal

    80–100

    Markers sit in the range associated with the longest healthspan. We protect and maintain.

  • Watch

    60–80

    Trending, but not yet clinical. Caught here, most of it is reversible with the right plan.

  • Act

    below 60

    A clear signal that deserves attention now — long before it would surface as a diagnosis.

What we measure

Every system, in real numbers.

Six systems, measured in depth. Below is a sample of the live readouts a member sees — each value placed on its zone, read against the reference range, never left as raw lab jargon.

Optimal Watch Act

Sample readouts

ApoB

Optimal < 80 · borderline 80–100

64mg/dL
Optimal

Lp(a)

Optimal < 75 nmol/L

18nmol/L
Optimal

Coronary artery calcium

Zero score · no detectable plaque

0Agatston
Optimal

VO₂max

Top decile for age

48mL/kg/min
Optimal

Markers measured in this system

  • ApoB
  • Lp(a)
  • Coronary artery calcium
  • Blood pressure (24h)
  • VO₂max
  • Carotid intima thickness

The leading cause of preventable death — caught decades early.

Sample readouts

HbA1c

Optimal < 5.4% · pre-diabetic 5.7%+

5.2%
Optimal

Fasting insulin

Optimal 2–8 µIU/mL

6.1µIU/mL
Optimal

Visceral fat (MRI)

Watch 1.0–2.0 L · trending down

1.4L
Watch

Liver fat fraction

Watch 5–10% · target < 5%

4.8%
Watch

Markers measured in this system

  • HbA1c
  • Fasting insulin
  • HOMA-IR
  • Continuous glucose
  • Visceral fat (MRI)
  • Liver fat fraction

How your body handles fuel — the engine of aging.

Sample readouts

hs-CRP

Optimal < 1.0 mg/L

0.6mg/L
Optimal

IL-6

Watch 1.5–3.0 pg/mL

1.9pg/mL
Watch

Homocysteine

Optimal < 9 µmol/L

8.2µmol/L
Optimal

Gut microbiome diversity

92nd percentile · high diversity

92pct
Optimal

Markers measured in this system

  • hs-CRP
  • IL-6
  • Homocysteine
  • White cell differential
  • Gut microbiome diversity

The quiet driver behind most chronic disease.

Sample readouts

Vitamin D (25-OH)

Optimal 40–60 ng/mL

54ng/mL
Optimal

Omega-3 index

Optimal > 8% · cardioprotective

8.4%
Optimal

Thyroid (TSH)

Optimal 0.5–2.5 mIU/L

1.8mIU/L
Optimal

Ferritin

Watch 30–50 · target 50–150

46ng/mL
Watch

Markers measured in this system

  • Thyroid panel
  • Testosterone / estradiol
  • Cortisol rhythm
  • Vitamin D
  • Omega-3 index
  • Ferritin

The signals that govern energy, mood, and recovery.

Sample readouts

DEXA bone density (T-score)

Normal · above −1.0 SD

+0.4SD
Optimal

Lean mass index

Above age-matched median

19.2kg/m²
Optimal

Grip strength

Strong predictor of longevity

47kg
Optimal

Brain volume (vs age)

Above expected for age

+2.1pctl
Optimal

Markers measured in this system

  • DEXA bone density
  • Lean mass index
  • Whole-body MRI
  • Brain volumetrics
  • Grip strength
  • Gait & balance

Bones, muscle, brain, and the body that carries you.

Sample readouts

Epigenetic age (DNAm)

Biological age below chronological

−8.4yrs
Optimal

Telomere length

74th percentile for age

74pctl
Optimal

Glycan age

Inflammatory-aging marker

−3.1yrs
Optimal

Polygenic risk (composite)

Below-average inherited risk

Low
Optimal

Markers measured in this system

  • Epigenetic age (DNAm)
  • Telomere length
  • Polygenic risk scores
  • Glycan age
  • Skin & retinal age

Your true age — and where to spend your effort.

The assessment

One hour. The whole body.

A single, calm, non-invasive visit captures over twelve hundred data points. Hover a site to see what we measure there.

Optimal

Cognitive

MRI volumetrics, reaction time, processing speed

How it is captured

Whole-body MRI

No radiation, no contrast. Brain, organs, spine, and soft tissue at research resolution.

Cardiac imaging

Coronary calcium and structure — the earliest view of the leading preventable risk.

Complete blood draw

Over ninety markers in one sitting: lipids, metabolic, hormonal, inflammatory, nutrient.

Functional testing

VO₂max, grip, gait, balance, retinal and skin analysis — the body in motion, not just at rest.

A member entering AEVUM's non-invasive whole-body MRI scanner
Zero radiation · < 60 min
Evidence standard

Held to the standard of research,not marketing.

01

Validated reference ranges

Our zones are not the lab default. They are tuned to the ranges the longevity literature associates with the longest healthspan — and reviewed as the evidence moves.

02

Peer-reviewed methods only

Every assay, image protocol, and aging model we use is published and reproducible. If a marker is not backed by the science, it does not earn a place in your report.

03

A growing longitudinal cohort

Members who consent contribute, de-identified, to one of the largest prospective preventive-health datasets — which in turn sharpens every future reading.

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Cohort participants

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Published methods cited

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Research partnerships

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Assay reproducibility

Begin with a baseline

See the science applied to you.

One scan turns the research into your numbers — and the first point on a line you can move.